Results:Controlling for baseline cognitive deficit using the Blessed Orientation–Memory–Concentration test, Ba-
copaparticipants had enhanced AVLT delayed word recall memory scores relative to placebo. Stroop results were
similarly significant, with the Bacopagroup improving and the placebo group unchanged. CESD-10 depression
scores, combined state plus trait anxiety scores, and heart rate decreased over time for the Bacopagroup but in-
creased for the placebo group. No effects were found on the DAT, WAIS digit task, mood, or blood pressure. The
dose was well tolerated with few adverse events (Bacopan9, placebo n10), primarily stomach upset.