This process of exercise-induced adaptation in skeletal muscle fibers involves many signaling pathways that promote protein synthesis and the formation of new mitochondria (i.e., mitochondria biogenesis). In the next sections, we present a brief overview of the signaling processes that contribute to exercise-induced muscle adaptation. We begin with a “big picture” view of exercise-induced muscle adaptation to training. This is followed by a brief introduction to both the primary and secondary signaling molecules that participate in muscle adaption in response to endurance and resistance training. We than highlight the specific signals leading to muscle adaptation due to endurance exercise. Later, we discuss the signaling molecules responsible for muscle adaptation to resistance training.
Training Adaptation-Big Picture