The results were obtained 5 tons/ha of seaweed from the initial density of seaweed 1 ton/ha after 3 months of maintenance with daily growth rate of 4.18%/day. Vannamei shrimp growth of 0.5 gram to 16.7 gram/fish, shrimp production from 1 ton/ha to 3,5 tons/ha. Based on the economic analysis showed gain with the value of R/C ratio of 1.83 and Rentability of 80.08%. This research can be concluded that the presence of seaweed as biofilters generally will increase the specific growth rate of Vannamei shrimp. The biofiltration method is more likely, given the application is very simple, high adaptability, easy maintenance, and economic value increase.