This doctoral thesis is divided into two main parts: general part, which includes
current state of knowledge in the pediatric asthma field and personal study, which
includes both research on the monitoring of particulate matter pollution in urban areas
(Bucharest and Rosiori de Vede) as well as the assessment of asthma development in a
group of children included in the study, treated with different classes of asthma drugs and
its correlation with pollutant factors in the area and in the family environment.