The experimental results show that the local concentration of 5-HT is around several nM, which is consistent with those from other methods.
In addition, immunofluorescent imaging technique is utilized to confirm the functional existence of both type II and III cells in a cluster of isolated taste cells.
Different types of taste cells are labeled with corresponding specific antibody.
This 5-HT sensitive LAPS chip provides a potential and promising way to detect 5-HT and to investigate the taste coding and information communication mechanisms.