ฉันเป็นห่วงคุณDiscussion
Massage has been widely utilized for the alleviation of a
number of musculoskeletal disorders, including low
back pain and bone pain from metastatic malignancy
[3]. Despite its common utilization, studies showing
evidence of the beneficial effects of massage therapy are
still limited. Thai traditional massage has been shown to
reduce pain and muscle tension in patients with
scapulocostal syndrome [7]. Moreover, in a preliminary
study on the acute effects of Thai traditional massage
on biochemical markers of bone turnover, we demonstrated
that a single 2-hour session can acutely increase
serumP1NP,amarkerofboneformationby4.8%[6].
Using a randomized crossover design we demonstrated
in the present study that two sessions per week of Thai
traditional massage for 4 weeks resulted in a higher increase
in P1NP, particularly in older individuals with
smaller body built. The magnitude of change in P1NP
from Thai traditional massage was comparable to the
change in serum alkaline phosphatase in a study using
vibration platform [8] but was much less than that
achieved with parathyroid hormone, a potent bone formation
agent used in the treatment of osteoporosis,
which usually reaches 100% or higher [9]. Osteocalcin
did not change significantly in the present study despite
the changes in P1NP. Studies with bone forming agents
such as parathyroid hormone and sclerostin monoclonal
antibody have shown that osteocalcin is a less sensitive
marker in response to treatments [10,11]. It is of note
that the effect of Thai traditional massage on bone for-
mation was more apparent in postmenopausal women