the above results, based upon purely clinical observations, would seem to support Allen's view that blueberry leaf extract has a stabilizing influence upon the carbohydrate tolerance of certain cases of diabetes. that is cannot take the place of insulin need not be gainsaid. but if it can be shown to permit to dosage or frequency of administration of insulin to be decreased,or cases, or allow for added carbohydrate intake without increasing insulin,its use is justified. judgment regarding the value of a therapeutic agent of this sort is truly difficult and one must weight the evidence carefully before arriving at conclusion.
the fallacy of basing opinions upon a small number of observation is also realized. As everyone familiar with the malady knows,the course of diabetes is variable. There exist all grades of severity between the case which can be readily controlled by minor dietary restrictions and that which cannot be balanced even with large doses of insulin. That carbohydrate tolerance does improve as a result of, or in spite of,insulin is common experience. An example is shown in Table V, in which the daily amount of insulin was reduced from fifty-five unit to zero in the course of about eight weeks had any treatment been employed other than that which was used in the cases, one might have been led to quite erroneous deduction.