The American Dairy Products Institute and the U.S. Dairy Export Council, filed a Generally Recognized as Safe (GRAS) notification for MPCs and MPIs in 2012 for use as food ingredients for functional or nutritional purposes in multiple food applications, except for infant formula. The Food and Drug Administration has acknowledged the MPC and MPI GRAS notification and does not appear to have any objections and, therefore, has opened the notification for public comments (GRAS Notice No. GRN 000504).