Thus, PGE2 production seems to be not affected
by elevated temperatures in the isthmus due to the
different cell type populations. In conclusion, HS is
suggested to not affect the secretary function of PGs in
the isthmic oviduct.
The overall findings suggest that HS upsets the balance
between PGE2 and PGF2a secretions, which would be
expected to decrease the motility of the oviductal
smooth muscle, which is important for gamete/embryo
transport. This could lead to the low fertility in cattle
in summer.