The
effect of different parameters such as high hydrostatic pressure (100–600 MPa), different solvents (ace-
tone, methanol, ethanol and water), ethanol concentration (0–100% mL/mL), pressure holding time (1–
10 min) and liquid/solid ratio (10:1 to 25:1 mL/g) were studied for the optimal caffeine extraction from
green tea leaves.