Thus, the cytotoxic activity of the extract for the HL-60 cells is due to a cumulative effect of the isolated antiproliferative substances including ursolic, 23-hydroxyursolic, oleanolic, and corosolic acids, orsellinic acid methyl ester,erythrodiol, and scopoletin. In addition, benzoic acid showed genotoxic effects in human peripherial blood lymphocytes and frequent
mitotic and chromosomal aberrations in the root tips of Allium sativum, hence, pointing to the genotoxic potential of the extract.