In all the groups, toxic changes, stress and changes in behaviour
were not observed. An increase in the body weights of the animals
in all the groups was observed, whereas in Group III (200mg/kg)
there was a gradual increase in body weight during the complete
course of the study. Hence, weight loss was not reported in any
of the group. Food intake and water intake were same in all the
groups. When compared to control, marked histological changes
were not observed in kidney and liver of the drug-treated groups
(Groups II–V). Acute toxicity studies showed nomortality, and normal
behaviour was observed in all the treated and control groups.