According to the study, one in five people in Taiwan suffers from joint cartilage disease. Joint cartilage is located on the joint contact surface of two bones, the main function is to withstand friction, compression stress and protect its lower structure. As a result, it is highly specific, but has limited supply of nerves, blood vessels and lymphas and lower metabolic activity. This vascular-free structure leads to a lack of precursor and nutrient cells, thus severely limiting the ability of cartilage to self-regenerate. Due to the lack of nerves and blood vessels, when feeling pain, usually has been damaged to the cartilage lower bone, so a slight cartilage defect is generally difficult to detect the current whether the use of drugs or surgical treatment can not fully restore the function and structure of cartilage. With the development of tissue engineering, the possibility of cartilage tissue regeneration and complete repair is raised. A new process for the preparation of liquid resin sin of a hydroxious polyurethane-based photosensitive material has been developed in this article, and the material has been applied to 3D-printed custom cartilage stents with high cell compatibility. It can therefore be considered that 3D printed hybrid stents may have potential in custom tissue engineering and can also promote the development of cartilage tissue engineering.
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