Seaweeds like Caulerpa lentillifera (lato) and Eucheuma denticulatum (guso) are used as main ingredient in Filipino delicacies popular here and abroad. They have been branded as healthy food being rich in dietary fiber, minerals, vitamins, proteins, phytochemicals, with low lipid content but rich in omega-3 fatty acids. Studies have shown that consumption of food rich in omega-3 fatty acids are essential for proper brain functioning and normal growth, and is associated with reduced risk of cardiovascular diseases. However like all marine organisms, there is also the risk of accumulation of heavy metals like cadmium which may lead to renal failure and bone demineralization. In this study, seaweeds samples collected from wet markets in Metro Manila during the months of June and October will be analyzed for their omega-3 fatty acid and cadmium content. Prior to extraction and analysis, samples were air-dried and then grounded. Lipids were extracted using a modified Folch method and analyzed via high performance liquid chromatography (HPLC) using fish oil available in local drugstores as standard. In the heavy metal analysis, samples were subjected to nitric acid digestion and cadmium concentration was analyzed using atomic absorption spectroscopy. HPLC chromatogram demonstrated the presence of a dominant peak in all samples that is similar to the fish oil standard, which could possibly correspond to a triacylglycerol with omega-3 fatty acids. To better assess the risks and benefits of seaweed consumption, further studies that will quantify the amount of omega-3 fatty acids and heavy metals in the seaweed samples are necessary.