Case presentation: A 40-year-old Indian man presented with an acute history of four episodes of seizures, fever,
headache, drowsiness, focal neurological deficits and vesicular eruptions over the abdomen in a typical dermatomal
distribution. His head computed tomography scan revealed multiple cerebral hemorrhages. Investigations (positive
ratio between the cerebrospinal fluid/serum quotients for anti-herpes zoster virus immunoglobulin G and total
immunoglobulin G antibodies) established its infective origin due to herpes zoster virus. He developed bilateral
pneumonia during the hospital course. He had an excellent recovery following a 2 weeks’ course of intravenous acyclovir.
Conclusion: Herpes zoster virus encephalitis or vasculopathy is a rare cause of multiple intracerebral hemorrhages and
must be considered in the differential diagnosis of patients presenting with an acute history of fever, altered
consciousness, and focal neurologic deficits with history of a typical herpetic rash. Its prompt recognition and treatment
could alter the course of illness.
Keywords: Diagnosis, Herpes zoster virus, Intracerebral hemorrhage, Vasculopathy, Viral encephalitis
Case presentation: A 40-year-old Indian man presented with an acute history of four episodes of seizures, fever,
headache, drowsiness, focal neurological deficits and vesicular eruptions over the abdomen in a typical dermatomal
distribution. His head computed tomography scan revealed multiple cerebral hemorrhages. Investigations (positive
ratio between the cerebrospinal fluid/serum quotients for anti-herpes zoster virus immunoglobulin G and total
immunoglobulin G antibodies) established its infective origin due to herpes zoster virus. He developed bilateral
pneumonia during the hospital course. He had an excellent recovery following a 2 weeks’ course of intravenous acyclovir.
Conclusion: Herpes zoster virus encephalitis or vasculopathy is a rare cause of multiple intracerebral hemorrhages and
must be considered in the differential diagnosis of patients presenting with an acute history of fever, altered
consciousness, and focal neurologic deficits with history of a typical herpetic rash. Its prompt recognition and treatment
could alter the course of illness.
Keywords: Diagnosis, Herpes zoster virus, Intracerebral hemorrhage, Vasculopathy, Viral encephalitis
การแปล กรุณารอสักครู่..
