If you are in your late 50’s or beyond, or if for some reason you have a condition that has rendered your pituitary incapable of a normal release of hGH, a great time to take hGH is right before bed. This allows you to closely mimic the natural pattern that would occur if your pituitary were functioning properly.
For those younger than mid-fifties, taking your hGH right before bed is going to end up creating a negative feedback loop, robbing you of your body’s own nightly pulse of hGH.
Yet another strategy should be considered if you are using insulin with your hGH. Insulin should be used immediately post workout. hGH and insulin do some great things together – they shuttle nutrients in a very complimentary way with each other, and the combination of hGH and Insulin create the best environment for IGF-1 production. If you are using insulin immediately post workout, this would be a great time to take a couple of units of hGH.