MoBa’s family design means that paternal, fetal and
maternal genes can be studied at the same time, opening
for studies of maternal-fetal interactions as well as
imprinting effects (a certain allele will only have effect
when it comes from one of the parents). In addition,
many MoBa mothers have participated with more than
one pregnancy. Women who have had pre-eclampsia
in one but not another pregnancy (discordant pregnancies)
are of special interest, since the maternal genome
is constant, but the fetal genome and environmental
influences differ.