Nevertheless, the required time-temperature
combination to eliminate or decrease any reasonably expected level
of Salmonella to a level that guarantees food safety depends upon several
factors, including the heat resistance of the microorganism, the
heat transfer rate and the distribution of the Salmonella in the food
(superficial or deep). The effectiveness of heat treatment on Salmonella
is also affected by product composition (fat content, NaCl, pH and
water activity) and geometry (volume and size)