Therefore, it was supposed that recrystallinity problems can be avoided by using Compritol 888 ATO as the SLN matrix (zur Mu¨hlen et al., 1998). This study focused on the investigation of the storage stability of the prepared SLN dispersions over 60 days as functions of storage time and temperature via rheological and morphological means. An attempt was made to explain the observed differences in viscoelastic behavior on a physical base. Furthermore, we demonstrate how rheological methods can be employed for determining the storage stability of the dispersed colloidal drug carriers.