Ascorbic acid (vitamin C) may acid in converting methemoglobin to Oxyhemoglobin (30 mg/kg q6–12h PO or IV.)
Cimetidine, an H2-receptor antagonist, is an inhibitor of cytochrome P-450 oxidase,reduce the metabolism of acetaminophen to NAPQI(5 to 10 mg/kg PO,IM, or IV q6–8h.)Combination of cimetidine with NAC and ascorbic acid.