The xylose-lysine MRPs were prepared by refluxing D-xylose and L-Iysine
monohydrochloride (molar ratio, 1 :2) at 100°C and pH 9.0 for IOh. 9) In
a model system, glycine (7 mmol), creatinine (7 mmol), D-glucose (3.5
mmol), and different doses (I, 2, 5, and IOmg) of xylose-lysine MRPs
wererefluxed in diethyl-glycol (2IOml) containing 14% (v/v) water at
128°C for 2 h. 4 ) In a control group, no xylose-lysine MRPs were added