In a later placebo study involving 147 arthritis patients, they were given either shark cartilage or a placebo. Those with the placebo were encouraged to use other treatments when their pain became severe. After five years the placebo group reported a 5% drop in pain scores compared to 85% of the group taking shark cartilage. The joint deterioration in each group was assessed, and was considerably less in the cartilage group, who also lost less time at work through pain.