This study assesses the relationship between global sea surface temperature (SST) and a regional index of rainfall (NWPR) in Piura-Tumbes, a coastal region in northwestern Peru, over the period 1965–2008 by means of the Pearson product-moment correlation. The results show that this area is strongly influenced by three indices: El Niño-Southern Oscillation (ENSO) Niño3.4 region, the Indian Ocean Dipole (IOD), and the equatorial Atlantic Oscillation (ATL3). In particular, a POSITIVE correlation has been found with the two first indices (Niño3.4 and IOD) and a negative one with ATL3 with several months of delay. This allows developing a forecast regression model for monthly rainfall in NW Peru with months in advance. The results show that linear regression model is not enough to provide satisfactory results; however, a nonlinear regression model improves considerably the prediction of rainfall anomalies in NW Peru.