Atenolol (ATL) is an antihypertensive, antianginal, and
antiarrhythmic drug; chemically it is 4-(2-Hydroxy-3-
isopropyl aminopropoxy)-phenyl acetamide [9,10]. It is
mainly act by inhibition of rennin release and angiotensin-II
and aldosterone production. The Indian Pharmacopoeia
describes non-aqueous titration method for the assay of
atenolol. Extensive literature search revealed that there is no
validated spectrophotometric method reported for
simultaneous estimation of ATV and ATL in combined
dosage form and hence a successful attempt has been made in
the present work to estimate these two drugs simultanously
by spectrophotometric analysis.