Deka et al (2011) evaluated the increased production of cellulases from a strain of Bacillus subtilis by
optimizing the production medium. Therefore, the significance of each component's concentration was
evaluated and also determined the optimal concentration of statistically significant components. The peak
of activity was 430 U / L to 18 g / L of CMC, 8 g / L of peptone and 4.79 g / L of yeast extract. Although the
enzymatic activity was about 17 % higher than the one presented in this work, the production medium
used has a high cost due to high concentrations of CMC (80% higher), peptone and yeast extract (140%
higher), which is not interesting for industry.