Experimental model and animals
The experimental protocol of this study was
submitted to the Committee on Animal Research andEthics (CEUA), Federal University of Rio Grande do
Norte - UFRN. For the development of the protocol
No. 021/2011 we adopted the ethical principles and
procedures according to the Standard Guide for
Care and Use of Laboratory Animals (1996). This
study was conducted in the Laboratory and Animal
Facility of the Department of Biochemistry, Federal
University of Rio Grande do Norte-UFRN.