The National Asthma Education and Prevention Program (NAEPP) of the National Heart, Lung, and Blood Institute (NHLBI) has published comprehensive guidelines for diagnosing and managing asthma. The most recent guidance was published in 2007 (previous versions were published in 1991, 1997, and 2002): Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma is also known as EPR-3.2 This guideline provides treatment recommendations with the strength of the evidence base for children 0–4, 5–11, and >12 years of age and adults. EPR-3 is based on a systematic review and expert opinion.