DHEA is a known Raf/MEK/ERK signaling pathway activator, we studied the role of this pathway
on HSV-1 infection. ERK1/2 phosphorylation was stimulated in HSV-1 infected cultures. UO126, a Raf/
MEK/ERK signaling pathway inhibitor, impaired viral multiplication, while anisomycin, an activator of
this pathway, enhanced it.
DHEA is a known Raf/MEK/ERK signaling pathway activator, we studied the role of this pathwayon HSV-1 infection. ERK1/2 phosphorylation was stimulated in HSV-1 infected cultures. UO126, a Raf/MEK/ERK signaling pathway inhibitor, impaired viral multiplication, while anisomycin, an activator ofthis pathway, enhanced it.
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