Antiochic acid1and its biosynthetically related polycyclic
diterpenes represent a vast multitude in the fascinating realm
of terpenoids.
1
Furthermore, they have interesting structures
and biological activities (Scheme 1).
1,2
The antiochic acid1
possessed several synthetic challenging structural features,
including multisubstituted tricyclic core, two quaternary
chiral centers, and the styrene type side chain. Although
several racemic syntheses of abietane diterpenes have been
reported,
3,4
antiochic acid1had not surrendered to any total