Antisolvent crystallization is a material-induced crystalliza-tion technique that uses an antisolvent to induce particle
precipitation (Mostafa Nowee et al., 2008; Yang and Nagy,
2014). When compared to an energy-induced crystallization
process such as evaporative crystallization, the antisolvent
crystallization does not use heat energy and therefore elim-inates the degradation of heat-sensitive materials such as
foods and drugs. Therefore, the technology can be success-fully applied to recrystallization and particle size reduction of
biologically active ingredients, which is one of the major inter-ests in pharmaceutical industries