Process Route 3 (Fig. 4)
This process route consisted of fed-batch fermentation with
in situ product recovery by gas-stripping, followed by LLE (with
2-ethyl-1-hexanol as extractant), and steam stripping distillation
(Fig. 4). The C. beijerinckii BA101 fermentation strain was used in
this design, which will be referred to in future as ‘‘Process Design
3’’. The overall design of this process was based on Bohlmann
[28], while the fed-batch fermentation and in situ gas stripping
were based on the laboratory research results by Ezeji et al. [4].
The downstream processing design was the same as the optimal
flow sheet proposed by Liu et al. [13]. The LLE process was based
on similar unit operations simulated in process designs by various authors [1,12,13]. Different with the molasses feed stream of Process
Routes 1 and 2 (all set at 147.21 ton/h), the molasses feed
stream for this process design was set at 35.28 ton/h in order to
achieve a final product stream that is of comparable magnitude
to the other process designs.
Process Route 3 (Fig. 4)This process route consisted of fed-batch fermentation within situ product recovery by gas-stripping, followed by LLE (with2-ethyl-1-hexanol as extractant), and steam stripping distillation(Fig. 4). The C. beijerinckii BA101 fermentation strain was used inthis design, which will be referred to in future as ‘‘Process Design3’’. The overall design of this process was based on Bohlmann[28], while the fed-batch fermentation and in situ gas strippingwere based on the laboratory research results by Ezeji et al. [4].The downstream processing design was the same as the optimalflow sheet proposed by Liu et al. [13]. The LLE process was basedon similar unit operations simulated in process designs by various authors [1,12,13]. Different with the molasses feed stream of ProcessRoutes 1 and 2 (all set at 147.21 ton/h), the molasses feedstream for this process design was set at 35.28 ton/h in order toachieve a final product stream that is of comparable magnitudeto the other process designs.
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