In the same time period, volunteers who used the con-
trol cream exhibited random variations in sensitivity limits
depending on the time point (decrease at D29, then
increase at D57) clearly reflecting a random placebo-like
pattern (cf. Fig. 3). In contrast, during treatment with the
BL lysate, skin sensitivity regularly and significantly
decreased at all time points in the group applying the test
cream. These clinical findings suggest that BL bacterial
extract may prevent negative environmental effects (cold in
winter, air dryness). Indeed, skin sensitivity measurements
at the end of treatment time showed values close to normal
as commonly found in subjects with non-sensitive skin.
It seems that topical application of BL preparation
contributes to reinforce skin homeostasis and to improve
skin resistance to external abuse