Wirzinger et al. [58] detected a more pronounced relation
between the amount of sewage and level of genotoxic
damage in field-collected three-spined sticklebacks.
Bagdonas et al. [59] detected higher frequencies of MN
in different fish species collected from the polluted sites
of Nemunas River, Lithuania. In finally Ali et al. [18] and
Osman et al. [60] suggested that the micronucleus test in
fish erythrocytes as a sensitive monitor for aquatic
pollution. A study carried out by Ergene et al. [61]
suggested that the genotoxic effects observed in
erythrocytes of fishes exposed to the Goksu Delta
(Turkey) are generally correlated with heavy metal content
of water samples. Therefore, we can suggest that the
induction of cytogenetic damage can be due, at least for
this analysis, to the presence of heavy metals in the
refinery effluent. The results of this study confirm the
usefulness of the erythrocyte MN and RAPD-PCR as
powerful monitoring tools for detecting genotoxic agents
in water environment.