The present work revealed increase in the interfollicular spaces and disruption of the basal lamina of follicles and these findings were coincided with other studies [23]. The latter reported decrease in the size of follicles and widening of the interfollicular spaces and attributed this widening to disruption of the connective tissue. At the end they concluded that Cr(VI) is potentially toxic to the thyroid gland. Also, another studies found the same results with irregularity and shrunken of some follicular cells increase in the number of disorganized and collapsed follicles. Hyperplasia of follicular cells and nuclei appeared oval, rounded, irregular and even shrunken. They added that disruption of the apical and basal laminae were seen [24].