This study aims to investigate the teachers’ perceptions of the barriers and challenges preventing teachers to integrate ICT in the classroom. Therefore, a validated questionnaire was administered to 30 high school English teachers who were selected from the five main educational districts in the city of Isfahan, Iran. Stratified random sampling was used to select equal number of respondents from each educational district. The findings indicated that although teachers had a strong desire to use ICT in the classroom, they were encountered with some barriers. Insufficient technical supports at schools and little access to Internet and ICT were considered as the major barriers preventing teachers to integrate ICT into the curriculum. Moreover, the descriptive analysis of the results showed that shortage of class time was another significant barrier discouraging teachers to use ICT into the classroom.