The most common types of hearing loss are presbycusis (due to aging) and noise-induced hearing loss (NIHL).NIHL is due to continued exposure to loud noise levels, resulting in gradual loss of auditory acuity and is usually bilateral,symmetric, sensorineural and irreversible. It usually affects the high audiometric frequencies of 3000---6000 Hz.The etiology of hearing loss also has genetic components, in addition to environmental ones, and more recently, inner ear inflammatory response induction and up-regulation of proinflammatory cytokines were evaluated in the presence of exacerbated noise.5---Several researchers have reported the presence of inflammatory cells in the steady state and their increase after lesions in the inner ear.