Residual renal function is known to be an important determinant
of serum b2-microglobulin level and a contributor of b2-
microglobulin clearance in patients with HD [10,11]. In patients
with greater residual renal function, the beneficial effects of b2-
microglobulin removal by high-flux dialysis may not be apparent.
Therefore, it may be postulated that the beneficial effect of highflux
dialysis on mortality may be different between patients with
different degrees of residual renal function.
This study aimed to determine the interaction of residual renal
function with dialyzer membrane flux on mortality in patients
enrolled in the Clinical Research Center (CRC) registry for ESRD
cohort which is an observational prospective cohort study
conducted in Korea.