The Piglets at 21th day after administration, 3 head per group were autopsy. Bleeding blood from artery and vein . Weighing heart, liver, spleen, kidney and adrenal gland, and calculates the organ / body weight ratios. For (adrenal gland and kidney) organ located on the left and right sides, and carried out left and right individually measure, is calculated by adding up the weight ratio. After weighting fixed the organs and tissues in 10% neutral buffered formalin solution.