According
to the Dutch RIVM report 71041018 issued in
1992, the safety limit of intravenous exposure (and
inhalation) to formaldehyde residues was calculated
at 16.8 mg. This value is based on the LD50
values calculated in several animal species and
exposure routes. Such calculation takes into
account a safety margin of 250 to translate from
animal data to one-time exposure in humans. On
the other hand, the mean safety limit value was set
at 200 mg in EN14180, which is approximately 80
times lower than the limit for intravenous
exposure. It is noteworthy that the amount of
formaldehyde residue in the oxygen tubing
exceeded 200 mg in our study.