Ingredients: Fresh buffalo’s milk was obtained from the herd of the dairy cattle at Faculty of Agriculture, Ain Shams University, Egypt. Skim milk powder (SMP) (97% DM) made in Poland was obtained from the local market of Cairo. Whey powder (WP) containing 11% proteins, was purchased from Green Land for Food Industries 10 of Ramadan City, Egypt. The full ripe pomegranate fruit wonderful variety and mango fruit zebda variety were obtained from the local market. Sodium carbonate and methanol were obtained from El-Gomhoreya Co., Cairo, Egypt. 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH), Gallic acid and Folin-Ciocalteus phenol reagent was purchased from Sigma–Aldrich Inc.