The present paper sought to identify what perception teachers from Natural Science fields have on the use of instructional
strategies that make use of models to represent biomolecules. The data presented are related to two continuing education courses
carried out with teachers from public schools of the state of São Paulo (Brazil). Such data showed that the teachers approved the
use of instructional materials such as the ones suggested in the courses (e.g., construction of a 3-D biomolecular structure) and
they pointed out some advantages and obstacles to the use of such materials.