Difficulty to follow instruction in this context can be defined as the students’ problem in following the experimental procedure methodically. The common mistake that most students demonstrated during transition was using the unmeasured volume of water when the instruction clearly required them to do so. The problem with following instructions also occurred in the context where students were supposed to stir the solution before taking the temperature so that the heat would be evenly and uniformly distributed. In primary school, only one student was able to follow this step every time she took the water temperature during heating, and she continued the practice through secondary school. Some of the students followed the instruction, however, they used the thermometer to stir the liquid. In using the microscope, the students again did not follow the instruction given in MSTT. Some of the students overlooked the step, especially when it involved staining of the specimen on the microscope slide so that it could be better viewed. For example during observation of the third task in MSTT, Student 4; placed the glass slide cover on the specimen. It seemed as she forgot to put the iodine solution. She pressed the glass slide with her finger. She read the given worksheet and realized that she had skipped the important step (Obs.3, Ep1, S4b)