Furthermore, correlations between some other amino acids and the expression level in specific tissues are interesting. For example, according to our results, amino acid asparagine has a positive correlation with the expression level of tumor suppressor gene in ovary, nerve tissues, and embryonic tissues. There are some evidences about the role of this amino acid in the control of the cell growth. It has been reported that asparagine synthetase is a potential biomarker in ovarian cancer (Lorenzi and Weinstein, 2009). Also, it is known that asparagine can be the inductor of apoptosis in nervous tissue (Chalisova et al., 2002). These data may support the importance of this amino acid in the regulation of tumor suppressor gene expression.