Yes, more than likely. For professionals.
But for a hobbyist such as myself, Animate Pro 3 is as far as I go with Toon Boom. I cannot afford or justify upgrading to Harmony. Essentials is a waste of time and Premium is my only upgrade path option and I can't afford it.
Anime Studio Pro has just added frame-by-frame capability in version 11. I think I'll stick with them. It's a LOT more affordable.