Abstract. The first two cases of rhinoentomophthoromycosis to be recognized in Costa
Rica are reported. The first patient was a 32-year-old Caucasian male from the Pacific Coast,
and the second, a 17-year-old Negro male from the Atlantic Coast. Both cases showed the
typical involvement of the nasofacial skin with the formation of subcutaneous nodules. One
patient also showed left maxillary sinus involvement. Both patients were in general good
health, without any associated disease. Cultures from the second patient, taken from the
glabellar nodule, were positive for Conidiobolus coronatus. These two cases represent the
first documentation of this uncommon mycosis in Central America.