4. Conclusions
Although it is possible to apply SERS technology coupled with chemometric models for qualitative and quantitative determination of carbamate pesticides in apples, it is still very challenging to apply the method for rapid analyses of residual compounds in complex food matrices. There are various components in food matrices that unavoidably interfere with the analyses of targeted molecules. The non-targeted components may competitively adsorb onto the active surface of SERS substrate, and may also exhibit characteristic Raman scattering signals that make it difficult or impossible to interpret the spectra of targeted molecules. In addition, there are very limited choices of commercial SERS substrates at this point, and the relatively high cost of these substrates impedes the application of SERS method in food analysis. However, with the rapid development of nanotechnology, it is possible to obtain various affordable SERS substrates with high enhancement effects that could be used to selectively adsorb targeted molecules, which would make it possible to improve the SERS sensitivity, simplify sample preparation of complex food matrices, and cut the overall cost.
4. ConclusionsAlthough it is possible to apply SERS technology coupled with chemometric models for qualitative and quantitative determination of carbamate pesticides in apples, it is still very challenging to apply the method for rapid analyses of residual compounds in complex food matrices. There are various components in food matrices that unavoidably interfere with the analyses of targeted molecules. The non-targeted components may competitively adsorb onto the active surface of SERS substrate, and may also exhibit characteristic Raman scattering signals that make it difficult or impossible to interpret the spectra of targeted molecules. In addition, there are very limited choices of commercial SERS substrates at this point, and the relatively high cost of these substrates impedes the application of SERS method in food analysis. However, with the rapid development of nanotechnology, it is possible to obtain various affordable SERS substrates with high enhancement effects that could be used to selectively adsorb targeted molecules, which would make it possible to improve the SERS sensitivity, simplify sample preparation of complex food matrices, and cut the overall cost.
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