Shrilatha and Muralidhara have demonstrated the increased oxidative stress in the STZ-induced diabetic model which greatly participates in the development of spermatogenic dysfunction. The seed of the date palm tree (Phoenix dactylifera L.), which constitutes 10-15% of the fruit weight is a byproduct of date processing industries. With world production of dates reaching 9 million tons ~ 960 thousand tons of seeds are produced and being wasted or partly used as fodder, noncaffeinated coffee, or a source of dietary fibers.