Furthermore, we identified that treatment with PP resulted in
alteration of EMT-associated proteins with a significant increase in
epithelial marker, E-cadherin (1.8 to 4.2-fold, p
,
0.05) and a
decrease in mesenchymal markers, vimentin, slug and zeb1 in the
MDA-MB-231 cells (1.5–4.2 fold, p
,
0.05). To further elucidate
the relationship between FOXM1 on EMT reversal, we then