Building technology and customary building practices are strongly influenced by local conditions. If given a picture of a house, most people can identify the area of the world where the house is located.17,18 Even in the United States, regional climate-driven variation is seen in construction. For example, construction in Florida is dominated by concrete because builders expect termites, and buildings are subject to mold damage due to warmth and humidity. The response to climate change is expected to produce efforts for better energy efficiency and tighter housing. Most existing housing is built to be occupied 50 years into the future. Current housing contributes about one-fourth of the total greenhouse gas (GHG) production. A typical Midwest US house produces more than 10 tons of carbon dioxide a year from heating and cooling.19 To meet carbon dioxide reduction goals, experts at the Swiss Institute of Technology expect this will need to be cut by 80% in the next 50 years.20 As a result of this, housing is expected to undergo energy reduction retrofits that involve superinsulation strategies and reduced exchange of indoor/outdoor air. The respiratory effect on the home’s inhabitants is unclear; however, it will likely result in increased illness.