The main purpose of this quasi-experimental study was to determine if students’ vocabulary acquisition is enhanced with the picture word inductive model (PWIM), a research based method of vocabulary instruction (Calhoun, 1999). Additionally, this research sought to identify if performances on vocabulary measures are related to performances on comprehension measures. Further, the study examined if the use of the PWIM impacts vocabulary and/or comprehension scores. Finally, this research focused on the possibility of the influence of language status on vocabulary and comprehension skills.